Mount Vernon, the county seat, was still a small village. The total population of the entire county at the time was less than 10,000. A contemporary newspaper describes Knox County:
Knox county... is very near the centre of the state and is rapidly improving. No situation in all the west, could be selected more free from the ordinary causes of disease, or affording a better security for health. It is of easy access in every direction. The distance to Sandusky upon Lake Erie is one hundred miles to which place a stage coach runs constantly from Mount Vernon...The steam boats upon Lake Erie in their trips to and from Buffalo and Detroit touch constantly in Sandusky. In the other direction it is ninety miles to Steubenville on the Ohio and one hundred and thirty to Pittsburgh... The great National road...and the canal now constructing, which is designed to connect the waters of Lake Erie with the Ohio River... both pass within about twenty-five or thirty miles...
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